Breast cancer pros and cons

Context: Intraoperative radiotherapy IORT is an accepted standard treatment for early stages of breast cancer in the selected cases. Published results of two trials aimed at evaluating the local recurrence as the final outcome. These differences need to be further evaluated regarding the efficacy and beneficence of IORT. Objectives: The aim of this study is to further analyze the data of these two trials to confirm the strategy of IORT in breast cancer as boost or radical modality. All of the published data from these trials were gathered and their subjects were analyzed and compared.
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Breast Cancer Risk and Prevention

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Breast cancer screening - Benefits and risks - NHS

Prophylactic mastectomy may reduce your risk of breast cancer. Learn how doctors assess breast cancer risk and how prophylactic mastectomy may help prevent breast cancer. One such question is whether to have preventive mastectomy prophylactic mastectomy — surgery to remove one or both breasts in hopes of preventing or reducing your risk of breast cancer. Keep in mind that being identified as having high risk doesn't mean you're certain to get breast cancer. All it means is that your likelihood of developing the disease is several times higher than that of women with average risk.
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Pros and Cons of Calcium Supplements

By Lisa Rapaport , Reuters Health. Reuters Health - Many breast cancer patients may miss out on genetic tests that could help pinpoint the ideal treatment regimen at least in part because their surgeons are uncomfortable discussing the pros and cons of these tests, a U. Approximately one-third of patients receive genetic testing after a diagnosis of breast cancer, and testing with a multigene panel is rapidly replacing tests based on just two - BRCA1 and BRCA2 - that have long been linked to aggressive tumors, researchers note in JAMA Surgery. Current practice guidelines recommend genetic testing for breast cancer patients who have an elevated risk of genetic mutations based on age, family history, and tumor characteristics. Even though most patients will see a surgeon as they determine their ideal treatment regimen, little research to date has examined variation among surgeons on how often genetic tests get ordered, researchers note.
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However, in practice potential MRI applications are being discussed more controversially. Problems begin with the identification of those at particular risk, explains the expert explained. There are healthy women who are carriers of a high-risk gene, such as a mutation of the BRCA1 or BRCA2 gene, for whom the intensive, early diagnosis with MRI is the only sensible alternative to prophylactic surgery. It becomes more difficult for those who are either at moderate genetic risk or not at genetic risk but at known familial risk. The question is, where do you set the threshold for individual risk which necessitates more intensive monitoring?
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